Measurements of the abundance of anhydrite and pyrite veins and the distribution of alteration types in oceanic basement enable estimates of global mass and isotopic fluxes of sulfur during hydrothermal alteration of oceanic crust. Fluxes of 2.5X10 (super 12) g/yr S (delta (super 34) S = 2.7 per mil) from the volcanic section to seawater and 2.1X10 (super 12) g/yr of seawater S (21 per mil) into the crust result in an insignificant change in the S content of altered ocean crust. These are clearly second-order fluxes compared to the riverine input of S to the oceans and the output of sedimentary pyrite. Most of the anhydrite that forms in the high-temperature axial convection cell must later be dissolved at lower temperatures during off-axis circulation. The mean delta (super 34) S of altered oceanic basement is 0.9 per mil, only slightly changed from the primary value of 0.1 per mil. Unless S is preferentially mobilized from (super 34) S-rich sulfide deposits or mineralized zones, subduction of altered basaltic crust is unlikely to be the source of high delta (super 34) S values of arc volcanic rocks ( approximately 4 per mil), but could contribute to isotopic heterogeneities of S in the mantle.