Understanding how pelagic sediment has been eroded, transported, and deposited is critical to evaluating pelagic sediment records for paleoceanography. We use digital seismic reflection data from an Integrated Ocean Drilling Program site survey (AMAT03) to investigate pelagic sedimentation across the eastern-central equatorial Pacific, which represents the first comprehensive record published covering the 18-53 Ma eastern equatorial Pacific. Our goals are to quantify (1) basin-hill-scale primary deposition regimes and (2) the extent to which seafloor topography has been subdued by abyssal valley-filling sediments. The eastern Pacific seafloor consists of a series of abyssal hills and basins, with minor late stage faulting in the basement. Ocean crust rarely outcrops at the seafloor away from the rise crest; both hills and basins are sediment covered. The carbonate compensation depth is identified at 4440 m by the appearance of acoustically transparent clay intervals in the seismic data. Overall, we recognized three different sedimentation regimes: depositional (high sedimentation rate), transitional, and minimal sedimentation (low sedimentation rate) regimes. In all areas, the sedimented seafloor mimics the underlying basement topography, although the degree to which topography becomes subdued varies. Depositional regimes result in symmetric sedimentation within basins and subdued topography, whereas minimal sedimentation regimes have more asymmetric distribution of sediments within topographic lows and higher seafloor relief. Regardless of sedimentation regime, enhanced sediment deposition occurs within basins. However, we observe that basin infill is rarely more than twice as thick as sediment cover over abyssal hills. If this variation is due to sediment focusing, the focusing factor in the basins, as measured by (super 230) Th, is no more than a factor of approximately 1.3 of the total vertical particulate rain.